In the United States, Black women are disproportionately affected by adverse sexual and reproductive health outcomes compared with women of other races and ethnicities. They have elevated rates of STI acquisition, and they are five times as likely as White women to become infected with chlamydia and gonorrhea. Although HIV infection rates among U.S. women have decreased over the past decade, Black women continue to be disproportionately affected. They have the second‐highest rate of new HIV infections after men who have sex with men, and are diagnosed at higher rates than are women of all other racial and ethnic backgrounds. In addition, while rates of unintended pregnancies and resulting births have decreased among women of all racial and ethnic groups, the proportion of pregnancies that are unintended has remained highest among Blacks (64%, vs. 38% among Whites). Disparities in contraceptive use have also been documented: Black women have higher rates of nonuse, and use less effective methods, than White women. All of these disparities in sexual and reproductive health outcomes demonstrate the necessity of novel and innovative interventions tailored to the needs and experiences of Black women. Such interventions can be pivotal in reducing existing disparities and improving sexual and reproductive health outcomes.